Current Project(s)
Molecular Communication
More information to be added when the project will start
Read More...Simulations of Lipid Phases
In collaboration with the Institut Charles Sadron (Strasbourg, FR), I am investigating the thermodynamic properties of lipid membranes generated by molecular dynamics (MD) simulations. My specific interest are the phase transitions and separations that can occur when the temperature of the system vary. Using Machine Learning to analyse the lipid configurations, we aim at describing complex lipid mixtures and phases using a two-state approach.
Read More...Collaborations
I am currently working in close collaboration with Drs. Celine Ruscher, Olivier Benzerara and Fabrice Thalmann from the Institut Charles Sadron (CNRS, Universite de Strasbourg, FR) for the study of lipid bilayers in Molecular Dynamics (MD) simulations using Machine Learning. We are often supported on this project by Drs. Carlos M. Marques and Adrien Gola, also from the Institut Charles Sadron, and by Dr. Tiago Espinosa de Oliveira (BR). For more information on this collaboration, please check the section Simulations of Lipid Phases above.
Publications
Peer-Reviewed Journals
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Real-Time Monitoring and Control of Nanoparticle Formation
Guo et al. 2023 JACS -
Ripple-like instability in the simulated gel phase of finite size phosphocholine bilayers
Walter et al. 2021 BBA - Biomembranes -
MLLPA: A Machine Learning‐assisted Python module to study phase‐specific events in lipid membranes
Walter et al. 2021 J Comp Chem -
A machine learning study of the two states model for lipid bilayer phase transitions
Walter et al. 2020 PCCP 22, 19147-54 -
Interaction of Giant Unilamellar Vesicles with the Surface Nanostructures on Dragonfly Wings
Cheeseman et al. 2019 Langmuir 35 (6), 2422-30 -
Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes
Weinberger et al. 2017 Sci Rep 7, 43963
Thesis
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Lipid Membrane Interactions with Self-Assembling Cell-Penetrating Peptides
PhD Thesis 2017 -
Construction de multicouches de graphène, polyélectrolytes et nanoparticules d'oxydes métalliques pour la création de supercondensateurs
MSc Thesis 2014 -
Etude de la photo-oxydation de lipides par FRAP ET FRAPP
MSc Thesis 2012
Previous Work
Previous Collaborations
Through my project on iSCAT, I joined a collaboration between the King’s College London and the Prof. Rachel O’Reilly and Dr. Jeffrey Foster from the University of Birmingham (Birmingham, UK). Through this collaboration, we aimed at imaging polymers with our iSCAT microscope and study their properties.
I have worked previously with Drs. Samuel Cheeseman and Vi Khanh Truong from Prof. Elena P. Ivanova group at the Swinburne University of Technology for the study of the interactions of Giant-Unilamellar Vesicles (GUVs) with Dragonfly wings. The results on this collaboration were published in Langmuir.
My PhD thesis was part of a collaboration with Prof. Ashutosh Chilkoti and Dr. Sarah MacEwan from Duke University, USA) to study how temperature could trigger the cellular uptake of cell-penetrating peptides (CPP) via self-assembly of elastin-like polypeptides (ELP) with the temperature. More details on the project can be found here.